Our ServicesPre-implantation Genetic Testing

Pre-implantation Genetic Testing

Pre-implantation Genetic Testing for Aneuploidies – Abnormal Number of Chromosomes (PGT-A) and Pre-implantation Genetic Testing for Monogenic Diseases /Chromosomal Structural Rearrangements (PGT-M/SR) (previously known as Pre-implantation Genetic Screening (PGS) and Pre-implantation Genetic Diagnosis (PGD))are an advanced technology and used as part of In Vitro Fertilization (IVF) for testing genetic diseases of embryos prior to the transfer to uterus.

Pre-implantation Genetic Testing for Aneuploidies – Abnormal Number of Chromosomes (PGT-A)
The aim of PGT-A is to determine if the embryo contains the wrong number of chromosomes prior to pregnancy, by employing the new technology “Next–Generation Sequencing (NGS)*” to test the full 46 chromosomes of the embryo.

PGT-A may contribute to:

• The selection of embryo with normal chromosome number for transfer to improve implantation
• The lowering of the risk of delivering a baby with common chromosomal abnormalities, such as Down syndrome PGT-A may be recommended for couples with:
  • Recurrent miscarriage
  • Repeated IVF / ICSI failure
  • Advanced maternal age
  However, women with poor ovarian response are not recommended because PGT-A may lower the chance of embryo transfer.

Pre-implantation Genetic Testing for Monogenic Diseases /Chromosomal Structural Rearrangements (PGT-M/SR)
PGT-M/SR is used to test for a specific genetic disease when one or both of the couple have a known genetic abnormality. PGT-M/SR helps couples not only to prevent the birth of a baby with a serious genetic disease, but also to avoid the physical and psychological trauma from termination of pregnancy.

PGT-M/SR may be recommended if the couples have:

• A serious genetic disease themselves or be carriers of that particular disease
• A family history of a serious genetic disease
• A child with a serious genetic disease

Alternatives
The alternative to PGT-A or PGT-M/SRis to undergo prenatal diagnosis during pregnancy or gametes donation. Please consult our doctors if you have any enquiries!

Cost
Fees for PGT-A and PGT-M/SR are in addition to the cost of the IVF cycle. Please contact our staff for details.

Under the laws of Hong Kong, Sex Selection is Prohibited,
except for the avoidance and prevention of a severe sex-linked genetic disease!